Our Methods
To study these complex internal states, we leverage multimodal monitoring to link symptoms to observable, quantifiable behaviors. We measure behavior alongside brain activity through intracranial electrophysiological monitoring in humans. Our research focuses on two patient populations: 1) ambulatory individuals implanted with recording-capable DBS devices, and 2) individuals in the inpatient setting undergoing intracranial monitoring.
Publications
Provenza NR, Reddy S, Allam AK, ..., Patel AB, Goodman WK, Sheth SA
Decoding Depression Severity From Intracranial Neural Activity.
Xiao J, Provenza NR, Asfouri J, ..., Bijanki KR, Pitkow X, Sheth SA
Biological Psychiatry, 2023 Sept 15.
Provenza NR, Sheth SA, Dastin-van Rijn EM, ..., Cohn JF, Goodman WK, Borton DA
Nature Medicine, 2021 Dec 9.